| Rotation | PICO/Mini-CAT | Question |
| Emergency Medicine | PICO #1 | For patients with acute migraines, does IV magnesium sulfate compared to standard pharmacological treatment (NSAIDs etc.) lead to adequate migraine relief? |
| Emergency Medicine | PICO #2 | In children presenting to the ER with a suspected limb fracture does immediate POC ultrasound for fracture diagnosis compared to traditional imaging (x-ray) result in equally accurate diagnosis? |
| Emergency Medicine | PICO #3 | In patients with recurrent nephrolithiasis and hypercalciuria identified in the emergency room, does dietary modification compared to standard medical management lead to a reduction in stone recurrence rates and improved long-term prevention? |
| Family Medicine | PICO #4 | In adult women, does the presence of herpes simplex virus type 1 increase the likelihood of developing Alzheimer’s disease compared to those without the virus? |
| Family Medicine | PICO #5 | In female patients, does dehydration significantly increase the risk of developing urinary tract infections (UTIs) compared to adequately hydrated patients? |
| Family Medicine | PICO #6 | In adults previously infected with chickenpox, does the Shingrix (recombinant adjuvant subunit) vaccine significantly reduce the risk of developing shingles and its complication of postherpetic neuralgia compared to those who do not receive the vaccine? |
| Surgery | Mini-CAT #1 | In postmenopausal women, does the implementation of cognitive behavioral therapy (CBT) or sleep restriction therapy (SRT) compared to sleep hygiene education (SHE) alone yield reduced insomnia symptoms and less day time sleepiness? |
| Pediatrics | PICO #7 | In infants, does the introduction of solid foods via baby led weaning as opposed to standard spoon feeding yield higher BMI and greater risk of obesity? |
| Pediatrics | PICO #8 | In adolescents with idiopathic scoliosis, what is the effectiveness of scoliosis-specific exercises compared to other conservative treatments in managing symptoms and preventing progression of the condition? |
| Pediatrics | PICO #9 | In children with molluscum contagiosum, how does the efficacy and safety of topical 10% potassium hydroxide compare to other or no treatment? |
| Ob/gyn | Mini-CAT #2 | In children, does allowing foods that contain artificial food colorings compared to restricting foods that contain artificial food colorings increase hyperactive behavior and rates of ADHD? |
| Internal Medicine | PICO #10 | In adults with acute hypercapnic respiratory failure due to COPD exacerbation, does initiation of BiPAP, compared to high-flow nasal cannula (HFNC) oxygen therapy, lead to greater improvement in arterial blood gases and reduced need for intubation? |
| Internal Medicine | PICO #11 | In patients with late-stage Hodgkin lymphoma, does treatment with ABVD chemotherapy compared to a more intensive regimen such as BEACOPP result in similar or better overall survival and progression-free survival rates? |
| Internal Medicine | PICO #12 | In adolescents, how do social media-assisted interventions compared to traditional health education methods affect HPV vaccination uptake and knowledge? |
